Murine Aseptic Surgical Model of Femoral Atrophic Nonunion

Aseptic nonunion of a femoral shaft treated using exchange nailing.

BACKGROUND There are many methods for treating femoral shaft aseptic nonunions of which exchange nailing is the simplest technique. However, the reported success rate varies. Therefore, a prospective study was conducted to further clarify the role of exchange nailing. METHODS From October 1994 through December 1999, 40 femoral shaft aseptic nonunions in 39 patients were treated using exchange...

Atrophic femoral bone nonunion treated with 1-84 PTH.

Vascularity in a new model of atrophic nonunion.

Our aim was to develop a clinically relevant model of atrophic nonunion in the rat to test the hypothesis that the vessel density of atrophic nonunion reaches that of normal healing bone, but at a later time-point. Atrophic nonunion is usually attributed to impaired blood supply and is poorly understood. We determined the number of blood vessels at the site of an osteotomy using immunolocalisat...

Reamed intramedullary exchange nailing: treatment of choice of aseptic femoral shaft nonunion

BACKGROUND The aim of this study was to evaluate a standardized method of treatment of femoral nonunion of the isthmal femur excluding non-united metaphyseal fractures. METHODS Between 2003 and 2010, 72 consecutive patients with nonunion of the femoral shaft were operated using a standardized protocol in our trauma department and followed up for successful union and functional result. RESUL...

Retrograde locked intramedullary nailing for aseptic supracondylar femoral nonunion following failed locked plating.

PURPOSE To review the outcome of retrograde locked nailing for aseptic supracondylar femoral nonunions following failed locked plating. METHODS Records of 20 men and 4 women aged 20 to 57 (mean, 39) years who underwent retrograde locked intramedullary nailing for aseptic supracondylar femoral nonunion following failed locked plating were reviewed. There were 20 closed and 4 open Gustilo type ...